Atherosclerosis and tumor suppressor molecules (Review)
نویسندگان
چکیده
منابع مشابه
Candidate Molecules as Tumor Suppressor for Human Uterine Mesenchymal Tumor
Uterine leiomyosarcoma (Ut-LMS) develops more often in myometrium of the uterine body than in the uterine cervix. The development of gynecologic tumors is often correlated with female hormone secretion; however, the development of Ut-LMS is not substantially correlated with hormonal conditions, and the risk factor(s) are not yet known. Importantly, a diagnostic-biomarker, which distinguishes ma...
متن کاملBRCA1 and p53 Tumor Suppressor Molecules in Alzheimer’s Disease
Tumor suppressor molecules play a pivotal role in regulating DNA repair, cell proliferation, and cell death, which are also important processes in the pathogenesis of Alzheimer's disease. Alzheimer's disease is the most common neurodegenerative disorder, however, the precise molecular events that control the death of neuronal cells are unclear. Recently, a fundamental role for tumor suppressor ...
متن کاملSubmembranous junctional plaque proteins include potential tumor suppressor molecules
T HE multistep theory of tumorigenesis is now widely accepted. During the tumor development the genetic alterations are accumulated, oncogenes are activated, and tumor suppressor genes are inactivated. Recently, the interesting idea is emerging that some cell adhesion molecules, integral membrane proteins, may work as tumor suppressors (Hedrick et al., 1993). Most of these cell adhesion molecul...
متن کاملCytomegalovirus Infection and Atherosclerosis: A Systematic Review
Cytomegalovirus (CMV) infection is one of the most common infections that affects humans’ cardiovascular system. Although the literature includes controversial evidence for any correlation between CMV infection and arterial atherosclerosis, the majority of studies, especially those with larger patient population and stronger data stand for such a relationship. However, the number of prospective...
متن کاملPentoxifylline Decreases Serum Level of Adhesion Molecules in Atherosclerosis Patients
Background: Inflammation is involved in development, progression, and complications of atherosclerotic disease. Clinical studies have indicated that the level of monocyte chemoattractant protein 1 (MCP-1), IL-18, and adhesion molecules correlates with the severity of atherosclerosis and can predict future cardiovascular events. Experimental studies have shown pentoxifylline (PTX) reduces these ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2014
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.2014.1866